1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration: APFIR2011
Program
The sessions are in English. : The sessions are in English.
The sessions are in Japanese. : The sessions are in Japanese.
Special Lectures   The sessions are in Japanese.  
Simultaneous interpretation will be provided from English to Japanese only.
At 16.00-17.00pm on June 2, 2011 (Thu.)
1. Innate Immunity and Inflammation
Shizuo Akira, WPI Immunology Frontier Research Center, Osaka University

At 17.00-18.00pm on June 2, 2011 (Thu.)
2. Induction of Pluripotency by Defined Factors
Shinya Yamanaka, Center for iPS Cell Research and Application, Kyoto University

At 18.00-18.30pm on June 2, 2011 (Thu.)
Three-Way Conversation   The sessions are in Japanese.
Simultaneous interpretation will be provided from English to Japanese only.
Speakers:
Shizuo Akira, WPI Immunology Frontier Research Center, Osaka University
Shinya Yamanaka, Center for iPS Cell Research and Application, Kyoto University
Toshikazu Yoshikawa, President, Kyoto Prefectural University of Medicine

Educational Lectures   The sessions are in Japanese.
At 14.00-14.50pm on June 2, 2011 (Thu.)
1. Prostaglandins and inflammation; a new concept arising from receptor-KO mouse studies
Shuh Narumiya, Dept. of Pharmacology, Kyoto University
At 14.55-15.45pm on June 2, 2011 (Thu.)
2. Cell Therapy for Heart Failure with Autologous Human Cardiac Stem Cells
Hiroaki Matsubara, Dept. of Cardiovascular Medicine, Dept. of Nephrology, Kyoto Prefectural University of Medicine
At 13.20-14.10pm on June 3, 2011 (Fri.)
3. Roles of Circadian Clock in Physiology and Pathophysiology
Hitoshi Okamura, Dept. of System Biology, Kyoto University
At 13.20-14.10pm on June 3, 2011 (Fri.)
4. Autoimmunity and Tolerance in Pemphigus
Masayuki Amagai, Dept. of Dermatology, Keio University

Main Symposia
At 09.30-12.00am on June , 2011 (Thu.)
1. Novel Targets for the Treatment of Inflammatory Diseases   The sessions are in English.
Chairpersons:
Kazuhiko Yamamoto, Dept. of Allergy and Rheumatology, The University of Tokyo
Yoshiya Tanaka, University of Occupational and Environmental Health
Speakers:
"Targeting Fc receptors"
   Toshiyuki Takai, Institute of Development Aging and Cancer, Tohoku University
"A mechanism regulating nucleic acid-sensing Toll-like receptor"
   Kensuke Miyake, The Institute of Medical Science, The University of Tokyo
"Targeting Interferon-alpha and IL-17 in Systemic Autoimmune Diseases"
Tsutomu Takeuchi, Division of Rheumatology, Dept. of Internal Medicine, Keio University
"Targeting the Jak STAT Pathway in T cell Biology"
   Arian Laurence, National Institute of Arthritis, Musculoskeletaland Skin Diseases National
   Institutes of Health

At 10.00-12.00am on June 3, 2011 (Fri.)
2. Hematopoietic and Mesenchymal Stem Cells   The sessions are in English.
Chairpersons:
Tatsutoshi Nakahata, Center for iPS Cell Research and Application, Kyoto University
Hideyuki Okano, Dept. of Physiology, Keio University
Speakers:
"Blood Generation from iPS Cells toward Clinical Applications"
   Koji Eto, Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine,
   Institute of Medical Science, The University of Tokyo
"Regulation of Hematopoietic Stem Cells in the Niche"
   Fumio Arai , Dept. of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology,
   School of Medicine, Keio University
"A model for chronic GVHD induced by minor antigen mismatched MSC Transplantation"
   Yumi Matsuzaki, Center for Integrated Medical Research, Keio University
"Disease Modeling of Human Immunological and Hematological Disorders with iPS Cells"
   Megumu Saito, Clinical Application Department, Center for iPS Cell Research and Application,
   Kyoto University

JSIR2011/APFIR2011 Joint Symposia

At 13.50-15.50pm on June 2, 2011 (Thu.)
1. Cellular and Molecular Bases for Fibrotic Diseases   The sessions are in English.
Chairpersons:
John Hamilton, Arthritis and Inflammation Research Center, The University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Australia
Kouji Matsushima, Dept. of Molecular Preventive Medicine, The University of Tokyo
Speakers:
"The LPA-LPA1 Pathway in Pulmonary and Dermal Fibrosiss"
   Andrew M. Tager, Massachusetts General Hospital and Harvard Medical School, USA
"Renal Fibrotic Diseases"
   Takashi Wada, Division of Nephrology, Dept. of Laboratory Medicine, Kanazawa University
"Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis"
   Yoh Takuwa, Dept. Of Molecular And Cellular Physiology Kanazawa University
"Roles of Prostanoids in Pulmonary Fibrosis"
   Toru Oga, Dept. of Respiratory Care and Sleep Control Medicine, Kyoto University

At 13.20-15.20pm on June 3, 2011 (Fri.)
2. Regenerative Medicine   The sessions are in English.
Chairperson:
Hideyuki Okano, Dept. of Physiology, Keio University
Speakers:
"Use of Human Induced Pluripotent Stem Cells (iPSC) to Model a Human Premature Aging Disease"
   Alan Colman, A*STAR Institute of Medica Biology, Singapore
"Rebuilding the Central Nervous System (CNS) with Pluripotent ES and iPS Cells"
   Dong-Wook Kim, Yonsei University College of Medicine/Korean Stem Cell Research
   Center, Korea
"Regeneration of the Damaged CNS Using Human iPSCs-Derived Neural Progenitor Cells"
   Hideyuki Okano, Dept. of Physiology, Keio University School of Medicine, Tokyo
"The Promise of Stem Cells as a Regenerative Approach for the Treatment of Multiple Sclerosis"
   Claude C.A. Bernard, Multiple Sclerosis Research Group, Monash Immunology and
   Stem Cell Laboratories, Australia
"The Roles of Notch and Hypoxia in Stem Cell Differentiation and Cellular Metabolism"
   Urban Lendahl, Karolinska Institute, Sweden

Symposia
At 14.00-15.45pm on June 2, 2011 (Thu.)
1. Regenerative Medicine Based on Biomaterials   The sessions are in English.
Chairpersons:
Masaya Yamamoto, Dept. of Biomaterials, Field of Tissue Engineering, Inst. for Frontier Med. Sci., Kyoto University
Richard OC Oreffo, Institute of Developmental Sciences, University of Southampton, UK
Speakers:
"Scaffold Design for the Reduction of Host Tissue Response for Regenerative Medicine"
   Gilson Khang, Dept. of BIN Fusion Technology & PolymerNano Science & Technology,
   Chonbuk National University, Korea
"Biomaterial-based Regenerative Therapy in Cardiovascular Field"
   Akira Marui, Dept. of Cardiovascular Surgery, Dept. of Experimental Therapeutics,
   Translational Research Center, Kyoto University Hospital
"Regenerative Medicine Using Biodegradable Gelatin Hydrogel in Orthopaedic Surgery"
   Ryosuke Kuroda, Dept. of Orthopaedic Surgery, Kobe University
"New Stem Cell, Nanotopography and Biomaterial Based Strategies for Skeletal Regenerative Medicine"
   Richard OC Oreffo, Institute of Developmental Sciences, University of Southampton, UK

At 14.00-15.45pm on June 2, 2011 (Thu.)
2. Tumor Microenvironment and Inflammation   The sessions are in English.
Chairperson:
Masataka Majima, Kitasato University School of Medicine
Raghu Kalluri, Harvard Medical School
Speakers:
"The Rate of Cancer Progression and Metastasis is Determined by the Tumor Microenvironment"
   Raghu Kalluri, Harvard Medical School
"Roles of Prostaglandins in Enhancement of Angiogenesis and Lymphangiogenesis during Tumor Development"
   Masataka Majima, Kitasato University
"Roles of Chemokines in Tumor Development and Progression"
   Naofumi Mukaida, Cancer Research Institute of Kanazawa University
"A Modulatory Role of Ras in VEGFR-3 Signalling during Normal and Pathological Lymphangiogenesis"
   Hirotake Ichise, Laboratory of Developmental Genetics, Center for Experimental Medicine and
   Systems Biology, the Institute of Medical Science, the University of Tokyo

At 14.20-15.50pm on June 3, 2011 (Fri.)
3. Stem Cell Biology for Disease Pathogenesis and Regenerative Medicine   The sessions are in Japanese.
Chairpersons:
Mineo Kurokawa, Dept. of Hematology & Oncology, The University of Tokyo
Atsushi Iwama, Dept. of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University
Speakers:
"TBA"
   Atsushi Iwama, Dept. of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University
"Cardiac Regeneration Using Direct Reprogramming Technology"
   Masaki Ieda, Dept. of Cardiology, Anatomy, and Physiology, Keio University School of Medicine
"Glim: a novel glioma-initiating marker"
   Toru Kondo, Dept. of Stem Cell Biology, Ehime Proteo-Medicine Research Center
"Regulation of Hematopoietic Stem Cells and Leukemia by Transcription Factors"
   Mineo Kurokawa, Dept. of Hematology & Oncology, The University of Tokyo

At 16.00-17.30pm on June 3, 2011 (Fri.)
4. Vascular Regeneration   The sessions are in Japanese.
Chairperson:
Ikuo Morita, Dept. of Cellular Physiological Chemistry, Tokyo Medical and Dental University
Jyun Yamashita, Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University
Speaker:
"Characterization of human vascular endothelial cells and pericytes for tissue engineering and angioplasty"
   Ikuo Morita, Dept. of Cellular Physiological Chemistry, Tokyo Medical and Dental University
"Polyphenic Significance of cAMP Signaling in Vascular Differentiation"
   Kohei Yamamizu, Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for
   Frontier Medical Sciences, Kyoto University / Dept. of Cell Growth and Differentiation, Center for
   iPS Cell Research and Application (CiRA), Kyoto University

At 14.20-15.50pm on June 3, 2011 (Fri.)
5. The Crosstalk between Various Gaseous Molecules and the Regulation of
    the Inflammation.  The sessions are in Japanese.
Chairpersons:
Makoto Suematsu, Dept. of Biochemistry and Integrative Medical Biology, Keio University
Yuji Naito, Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
Speakers:
"Carbon Monoxide Ameliorates the Intestinal Inflammation"
   Tomohisa Takagi, Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
"Mining the CO-sensitive Receptors by Affinity Purification"
   Yasuaki Kabe, Dept. of Biochemistry and Integrative Medical Biology, Keio University
"ROS signaling and its regulation by hydrogen Sulfide"
   Tomohiro Sawa, Dept. of Microbiology, Graduate School of Medical Sciences, Kumamoto University

At 16.00-17.30pm on June 3, 2011 (Fri.)
6. Bone Inflammation   The sessions are in English.
Chairpersons:
Hiroshi Takayanagi, Dept. of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
Masaru Ishii, Immunology Frontier Research Center, Osaka University
Speakers:
"Bone Remodeling Regulated by Osteoclast-derived Semapnorin 4D"
   Takako Negishi-Koga, Dept. of Cell Signaling, Graduate School of Medical and Dental Sciences,
   Tokyo Medical and Dental University
"Bone Marrow Niches for Hematopoietic Stem and Progenitor Cells"
   Takashi Nagasawa, Dept. of Immunobiology and Hematology, Institute for
   Frontier Medical Sciences Kyoto University
"Live Imaging of Bone Cell Dynamics"
   Masaru Ishii, Immunology Frontier Research Center, Osaka University
"Heterotopic Bone Formation and Muscle Regeneration"
   Takenobu Katagiri, Division of Pathophysiology, Research Center for Genomic Medicine,
   Saitama Medical University





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