Simultaneous interpretation will be provided from English to Japanese only.
At 16.00-17.00pm on June 2, 2011 (Thu.)
1. Innate Immunity and Inflammation
Shizuo Akira, WPI Immunology Frontier Research Center, Osaka University
At 17.00-18.00pm on June 2, 2011 (Thu.)
2. Induction of Pluripotency by Defined Factors
Shinya Yamanaka, Center for iPS Cell Research and Application, Kyoto University
At 18.00-18.30pm on June 2, 2011 (Thu.)
Three-Way Conversation
Simultaneous interpretation will be provided from English to Japanese only.
Speakers:
Shizuo Akira, WPI Immunology Frontier Research Center, Osaka University
Shinya Yamanaka, Center for iPS Cell Research and Application, Kyoto University Toshikazu Yoshikawa, President, Kyoto Prefectural University of Medicine
Educational Lectures
At 14.00-14.50pm on June 2, 2011 (Thu.)
1. Prostaglandins and inflammation; a new concept arising from receptor-KO
mouse studies
Shuh Narumiya, Dept. of Pharmacology, Kyoto University
At 14.55-15.45pm on June 2, 2011 (Thu.)
2. Cell Therapy for Heart Failure with Autologous Human Cardiac Stem Cells
Hiroaki Matsubara, Dept. of Cardiovascular Medicine, Dept. of Nephrology,
Kyoto Prefectural University of Medicine
At 13.20-14.10pm on June 3, 2011 (Fri.)
3. Roles of Circadian Clock in Physiology and Pathophysiology
Hitoshi Okamura, Dept. of System Biology, Kyoto University
At 13.20-14.10pm on June 3, 2011 (Fri.)
4. Autoimmunity and Tolerance in Pemphigus
Masayuki Amagai, Dept. of Dermatology, Keio University
Main Symposia
At 09.30-12.00am on June , 2011 (Thu.)
1. Novel Targets for the Treatment of Inflammatory Diseases
Chairpersons:
Kazuhiko Yamamoto, Dept. of Allergy and Rheumatology, The University of Tokyo
Yoshiya Tanaka, University of Occupational and Environmental Health
Speakers:
"Targeting Fc receptors"
Toshiyuki Takai, Institute of Development Aging and Cancer,
Tohoku University
"A mechanism regulating nucleic acid-sensing Toll-like receptor"
Kensuke Miyake, The Institute of Medical Science, The
University of Tokyo "Targeting Interferon-alpha and IL-17 in Systemic Autoimmune Diseases"
Tsutomu Takeuchi, Division of Rheumatology, Dept. of Internal Medicine,
Keio University
"Targeting the Jak STAT Pathway in T cell Biology"
Arian Laurence, National Institute of Arthritis, Musculoskeletaland
Skin Diseases National
Institutes of Health
At 10.00-12.00am on June 3, 2011 (Fri.)
2. Hematopoietic and Mesenchymal Stem Cells
Chairpersons:
Tatsutoshi Nakahata, Center for iPS Cell Research and Application, Kyoto University
Hideyuki Okano, Dept. of Physiology, Keio University
Speakers:
"Blood Generation from iPS Cells toward Clinical Applications"
Koji Eto,
Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine,
Institute of Medical Science, The University of Tokyo
"Regulation of
Hematopoietic Stem Cells in the Niche"
Fumio Arai , Dept. of Cell
Differentiation, The Sakaguchi Laboratory of Developmental Biology,
School
of Medicine, Keio University
"A model for chronic GVHD induced by minor
antigen mismatched MSC Transplantation"
Yumi Matsuzaki, Center for
Integrated Medical Research, Keio University
"Disease Modeling of Human
Immunological and Hematological Disorders with iPS Cells"
Megumu Saito,
Clinical Application Department, Center for iPS Cell Research and Application,
Kyoto University
JSIR2011/APFIR2011 Joint Symposia
At 13.50-15.50pm on June 2, 2011 (Thu.)
1. Cellular and Molecular Bases for Fibrotic Diseases
Chairpersons:
John Hamilton, Arthritis and Inflammation Research Center, The University of
Melbourne, Department of Medicine, Royal Melbourne Hospital, Australia
Kouji Matsushima, Dept. of Molecular Preventive Medicine, The University of Tokyo
Speakers:
"The LPA-LPA1 Pathway in Pulmonary and Dermal Fibrosiss"
Andrew M. Tager,
Massachusetts General Hospital and Harvard Medical School, USA
"Renal
Fibrotic Diseases"
Takashi Wada, Division of Nephrology, Dept. of
Laboratory Medicine, Kanazawa University
"Role of Lysophospholipid Mediator
Sphingosine-1-phosphate in Cardiac Fibrosis"
Yoh Takuwa, Dept. Of
Molecular And Cellular Physiology Kanazawa University
"Roles of Prostanoids
in Pulmonary Fibrosis"
Toru Oga, Dept. of Respiratory Care and Sleep
Control Medicine, Kyoto University
At 13.20-15.20pm on June 3, 2011 (Fri.)
2. Regenerative Medicine
Chairperson:
Hideyuki Okano, Dept. of Physiology, Keio University
Speakers:
"Use of Human Induced Pluripotent Stem Cells (iPSC) to Model a Human
Premature Aging Disease"
Alan Colman, A*STAR Institute of Medica Biology, Singapore
"Rebuilding the Central Nervous System (CNS) with Pluripotent ES and
iPS Cells"
Dong-Wook Kim, Yonsei University College of Medicine/Korean
Stem Cell Research
Center, Korea
"Regeneration of the Damaged CNS Using Human iPSCs-Derived Neural
Progenitor Cells"
Hideyuki Okano, Dept. of Physiology, Keio University
School of Medicine, Tokyo
"The Promise of Stem Cells as a Regenerative Approach for the Treatment
of Multiple Sclerosis"
Claude C.A. Bernard, Multiple Sclerosis Research Group, Monash Immunology and
Stem Cell Laboratories, Australia
"The Roles of Notch and Hypoxia in Stem Cell Differentiation and Cellular Metabolism"
Urban Lendahl, Karolinska Institute, Sweden
Symposia
At 14.00-15.45pm on June 2, 2011 (Thu.)
1. Regenerative Medicine Based on Biomaterials
Chairpersons:
Masaya Yamamoto, Dept. of Biomaterials, Field of Tissue Engineering, Inst.
for Frontier Med. Sci., Kyoto University
Richard OC Oreffo, Institute of Developmental Sciences, University of Southampton, UK
Speakers:
"Scaffold Design for the Reduction of Host Tissue Response for Regenerative
Medicine"
Gilson Khang, Dept. of BIN Fusion Technology & PolymerNano
Science & Technology,
Chonbuk National University, Korea
"Biomaterial-based Regenerative Therapy in Cardiovascular Field"
Akira Marui, Dept. of Cardiovascular Surgery, Dept. of
Experimental Therapeutics,
Translational Research Center, Kyoto University Hospital
"Regenerative Medicine Using Biodegradable Gelatin Hydrogel in Orthopaedic
Surgery"
Ryosuke Kuroda, Dept. of Orthopaedic Surgery, Kobe University
"New Stem Cell, Nanotopography and Biomaterial Based Strategies for Skeletal Regenerative Medicine"
Richard OC Oreffo, Institute of Developmental Sciences,
University of Southampton, UK
At 14.00-15.45pm on June 2, 2011 (Thu.)
2. Tumor Microenvironment and Inflammation
Chairperson:
Masataka Majima, Kitasato University School of Medicine
Raghu Kalluri, Harvard Medical School
Speakers:
"The Rate of Cancer Progression and Metastasis is Determined by the
Tumor Microenvironment"
Raghu Kalluri, Harvard Medical School
"Roles of Prostaglandins in Enhancement of Angiogenesis and Lymphangiogenesis
during Tumor Development"
Masataka Majima, Kitasato University
"Roles of Chemokines in Tumor Development and Progression"
Naofumi Mukaida, Cancer Research Institute of Kanazawa
University "A Modulatory Role of Ras in VEGFR-3 Signalling during Normal and Pathological Lymphangiogenesis"
Hirotake Ichise, Laboratory of Developmental Genetics, Center for Experimental Medicine and
Systems Biology, the Institute of Medical Science, the
University of Tokyo
At 14.20-15.50pm on June 3, 2011 (Fri.)
3. Stem Cell Biology for Disease Pathogenesis and Regenerative Medicine
Chairpersons:
Mineo Kurokawa, Dept. of Hematology & Oncology, The University of
Tokyo
Atsushi Iwama, Dept. of Cellular and Molecular Medicine, Graduate School
of Medicine, Chiba University
Speakers:
"TBA"
Atsushi Iwama, Dept. of Cellular and Molecular Medicine,
Graduate School of Medicine, Chiba University
"Cardiac Regeneration Using Direct Reprogramming Technology"
Masaki Ieda, Dept. of Cardiology, Anatomy, and Physiology,
Keio University School of Medicine
"Glim: a novel glioma-initiating marker"
Toru Kondo, Dept. of Stem Cell Biology, Ehime Proteo-Medicine
Research Center
"Regulation of Hematopoietic Stem Cells and Leukemia by Transcription Factors"
Mineo Kurokawa, Dept. of Hematology & Oncology, The
University of Tokyo
At 16.00-17.30pm on June 3, 2011 (Fri.)
4. Vascular Regeneration
Chairperson:
Ikuo Morita, Dept. of Cellular Physiological Chemistry, Tokyo Medical and
Dental University
Jyun Yamashita, Laboratory of Stem Cell Differentiation, Stem Cell Research
Center, Institute for Frontier Medical Sciences, Kyoto University
Speaker:
"Characterization of human vascular endothelial cells and pericytes
for tissue engineering and angioplasty"
Ikuo Morita, Dept. of Cellular Physiological Chemistry,
Tokyo Medical and Dental University
"Polyphenic Significance of cAMP Signaling in Vascular Differentiation"
Kohei Yamamizu, Laboratory of Stem Cell Differentiation,
Stem Cell Research Center, Institute for
Frontier Medical Sciences, Kyoto University / Dept. of
Cell Growth and Differentiation, Center for
iPS Cell Research and Application (CiRA), Kyoto University
At 14.20-15.50pm on June 3, 2011 (Fri.)
5. The Crosstalk between Various Gaseous Molecules and the Regulation of
the Inflammation.
Chairpersons:
Makoto Suematsu, Dept. of Biochemistry and Integrative Medical Biology, Keio University
Yuji Naito, Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
Speakers:
"Carbon Monoxide Ameliorates the Intestinal Inflammation"
Tomohisa Takagi, Molecular Gastroenterology and Hepatology,
Kyoto Prefectural University of Medicine
"Mining the CO-sensitive Receptors by Affinity Purification"
Yasuaki Kabe, Dept. of Biochemistry and Integrative Medical
Biology, Keio University "ROS signaling and its regulation by hydrogen Sulfide"
Tomohiro Sawa, Dept. of Microbiology, Graduate School
of Medical Sciences, Kumamoto University
At 16.00-17.30pm on June 3, 2011 (Fri.)
6. Bone Inflammation
Chairpersons:
Hiroshi Takayanagi, Dept. of Cell Signaling, Graduate School of Medical
and Dental Sciences, Tokyo Medical and Dental University
Masaru
Ishii, Immunology Frontier Research Center, Osaka University
Speakers:
"Bone Remodeling Regulated by Osteoclast-derived Semapnorin 4D"
Takako Negishi-Koga, Dept. of Cell Signaling, Graduate
School of Medical and Dental Sciences,
Tokyo Medical and Dental University "Bone Marrow Niches for Hematopoietic Stem and Progenitor Cells"
Takashi Nagasawa, Dept. of Immunobiology and Hematology,
Institute for
Frontier Medical Sciences Kyoto University
"Live Imaging of Bone Cell Dynamics"
Masaru Ishii, Immunology Frontier
Research Center, Osaka University
"Heterotopic Bone Formation and Muscle
Regeneration"
Takenobu Katagiri, Division of Pathophysiology, Research
Center for Genomic Medicine,
Saitama Medical University